Cardiovascular complications such as heart failure and stroke are the main causes of death in the Western world. Their incidences are still rising due to the aging of the population, obesity and, paradoxically, the successful treatment of acute myocardial infarction and cardiac arrhythmia. The acute occurrence/incidence of cardiac infarction, arrhythmia and stroke requires the restoration of vital functions in the human body with unduly delay. Research in order to prevent, diagnose and treat cardiovascular diseases is therefore of vital importance. This research master is focused on research questions aimed at the improvement of cardiac function in heart failure and the improvement of vascular function in metabolic diseases. Cardiovascular research is interdisciplinary by nature and flourishes by a close collaboration between clinical researchers and basic scientists. The clinical applications require background knowledge of physiology, anatomy, pathology, pharmacology and anaesthesiology as well as knowledge of the design of clinical trials and epidemiology. The interdisciplinary approach requires out of the box thinking and basic laboratory skills, combined with good communication with other scientists. During the courses and placements the intellectual attitude will be developed required to unravel mechanisms, their biological relevance and to find new therapeutics, in vitro, in animals and patients (form bench to bedside).